c-Kit Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: IHC;IF
Verified Samples |
Verified Samples in IHC: Human tonsil, Human liver, Rat colon |
Dilution | IHC 1:200-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse c-Kit |
Abbre | c-Kit |
Synonyms | C Kit, CD117, KIT, KIT oncogene, KIT proto oncogene receptor tyrosine kinase, Kit, Kit Ligand, MGF, Mast cell growth factor receptor, Mast/stem cell growth factor receptor Kit, PBT, Piebald trait protein, Proto oncog, Proto oncogene c Kit, c-Kit, c-Kit Ligand, p145 c-kit |
Swissprot | |
Cellular Localization | Cell membrane, Cytoplasm, Membrane. |
Concentration | 400 μg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Developmental Biology, Immunology, Neuroscience, Signal Transduction, Stem Cells, Tags and Cell Markers |
Conjugation | Unconjugated |
Background | This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |