CANX Polyclonal Antibody
Price:
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p;IF
| Verified Samples |
Verified Samples in WB: HCT116, HEK293, MCF-7, A549, K562 Verified Samples in IIHC: Human lung cancer Verified Samples in IF: Rat kidney |
| Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human Calnexin around the non-phosphorylation site of Ser583. |
| Abbre | Calnexin |
| Synonyms | CALX, CANX, CNX, Calnexin, FLJ26570, Histocompatibility complex class I antigen binding protein p88, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90 |
| Swissprot | |
| Calculated MW | 68 kDa |
| Observed MW | 90 kDa |
| Cellular Localization | Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Background | Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. |
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Selenoprotein F knockout leads to glucose and lipid metabolism disorders in mice
IF: 3.246Journal： JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2020)PMID：32995962Reactivity：MouseSample Type：Tissue homogenate
