CD54 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC;IF
Verified Samples |
Verified Samples in WB: Hela, HepG2, SW480, Human nasopharyngeal carcinoma, Mouse lung, Mouse kidney Verified Samples in IHC: Mouse kidney, Mouse liver Verified Samples in IF: Mouse lung |
Dilution | WB 1:1000-1:3000, IHC 1:500-1:1000, IF 1:200-1:800 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1 |
Abbre | CD54 |
Synonyms | Antigen identified by monoclonal BB2, BB 2, BB2, CD 54, CD54, CD_antigen=CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, Intercellular adhesion molecule, human rhinovirus receptor, intercellular adhesion molecule 1 (CD54) |
Swissprot | |
Calculated MW | 58 kDa |
Observed MW | 58 kDa |
Cellular Localization | Membrane |
Concentration | 0.84 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Immunology, Stem Cells |
Conjugation | Unconjugated |
Background | ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues . ICAM-1 is expressed by several cell types,typically on endothelial cells and cells of the immune system,and its expression can be up-regulated by various stimuli,including TNF-α,INF-γ,IL-1 and thrombin . It is a ligand for LFA-1 and Mac-1,serves as a receptor for rhinovirus,and is one of several receptors used by Plasmodium falciparum . |
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