Cleaved-CASP3 p17 (D175) Polyclonal Antibody（E-AB-30004）|-Elabscience伊莱瑞特【官网】

Cleaved-CASP3 p17 (D175) Polyclonal Antibody

说明书

Price: ¥2365.00 ¥1640.00 ¥1010.00 ¥420.00

Size:

200 μL 120 μL 60 μL 20 μL

Verified Samples	Verified Samples in WB: Hela, Mouse samples, Rat heart, Recombinant protein, Rat lung, Rat lung, Rat brain, Mouse colon, Mouse kidney Verified Samples in IHC: Human stomach cancer Verified Samples in IF: Rat liver
Dilution	WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Clonality	Polyclonal
Isotype	IgG
Immunogen	Synthesized peptide derived from the Internal region of human Caspase-3 p17
Abbre	Cleaved-Caspase-3 p17 (D175)
Synonyms	A830040C14Rik, Apopain, CASP-3, CASP3, CC3, CPP-32, CPP32, CPP32B, Casp3a, Caspase 3, Caspase-3 subunit p12, Cysteine p, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, apoptosis-related cysteine protease a
Swissprot	P42574
Calculated MW	32 kDa
Observed MW	20 kDa
Cellular Localization	Cytoplasm.
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4.
Purification Method	Affinity purification
Research Areas	Cancer, Cell Biology, Metabolism, Neuroscience
Conjugation	Unconjugated
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

Western Blot analysis of various cells using Cleaved-CASP3 p17 (D175) Polyclonal Antibody at dilution of 1:1000.

Immunohistochemistry of paraffin-embedded Human stomach cancer tissue using Cleaved-CASP3 p17 (D175) Polyclonal Antibody at dilution of 1:200.

Immunofluorescence analysis of Rat liver tissue using Cleaved-CASP3 p17 (D175) Polyclonal Antibody at dilution of 1:200.

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