FOXO3 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB: Jurkat Verified Samples in IHC: Rat brain |
Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthesized peptide derived from human FoxO3A around the non-phosphorylation site of Ser253. |
Abbre | FoxO3A |
Synonyms | AF6q21, AF6q21 protein, DKFZp781A0677, FKHR2, FKHRL 1, FKHRL1, FKHRL1P2, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1, Forkhead Drosophila homolog of in rhabdomyosarcoma , Forkhead box O3, Forkhead box O3A, Forkhead box protein O3, Forkhead box protein O3A |
Swissprot | |
Calculated MW | 71 kDa |
Observed MW | 97 kDa |
Cellular Localization | Cytoplasm>cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. |