GCG Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Mouse;Rat
- 应用性: IHC;IF
Verified Samples |
Verified Samples in IHC: Mouse pancreas Verified Samples in IF: Rat pancreas, Mouse pancreas |
Dilution | IHC 1:500-1:1000, IF 1:200-1:500 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Glucagon |
Abbre | GCG |
Synonyms | GCG, GLP 2, GLP1, GLP2, GRPP, GRPP Oxyntomodulin, Glucagon like peptide 1, OXM, Proglucagon, glucagon |
Swissprot | |
Cellular Localization | Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Metabolism, Developmental Biology, Signal Transduction, Stem Cells |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. |
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Pancreatic islet cells in microfluidic-spun hydrogel microfibers for the treatment of diabetes
IF: 9.400Journal: Acta Biomaterialia (2024)Reactivity:MouseSample Type:brown adipose tissue (BAT),Islet tissue