IFITM3 Polyclonal Antibody-Elabscience伊莱瑞特【官网】

IFITM3 Polyclonal Antibody

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货号：D-AB-10162L
说明书

说明书

Price: ¥2100.00 ¥800.00

Size:

100 μL 25 μL

宿主： Rabbit
反应性： Human;Mouse;Rat
应用性： WB;IHC;IF

Verified Samples	Verified Samples in WB: Human Hela, Human 293 T, Mouse Liver, Mouse Heart, Rat Liver Verified Samples in IHC: Rat kidney, Mouse lung, Human lung Verified Samples in IF: Human Hela
Dilution	WB 1:1000-1:2000, IHC 1:50-1:200, IF 1:100-1:400
Clonality	Polyclonal
Isotype	IgG
Immunogen	Recombinant Rat IFITM3 protein expressed by E.coli
Abbre	IFITM3
Synonyms	1 8U, Fragilis, IFITM3, IFM3, Interferon Induced Transmembrane Protein 3, Interferon Inducible Protein 15, Interferon Inducible Protein Homolog, Interferon induced transmembrane protein 3 (1 8U), Interferon inducible, Interferon inducible protein 1 8U, Interferon-i
Swissprot	P26376
Calculated MW	15 kDa
Observed MW	15 kDa
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method	Antigen Affinity Purification
Research Areas	Cancer, Developmental Biology, Stem Cells
Conjugation	Unconjugated
Background	IFITM3,also named as interferon-inducible protein 1-8U,belongs to the CD225 family. It is IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus,by inhibiting the early steps of replication. IFITM3 is identified as interferon-induced cellular proteins that restrict infections by retroviruses and filoviruses and of influenza virus and flaviviruses,respectively. IFITM3,the most potent antiviral IFITM,was found to inhibit an uncharacterized early infectious event after VSV endocytosis,but before primary transcription of its viral genome. IFITM proteins are viral restriction factors that can inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. They differentially restrict the entry of a broad range of enveloped viruses,and modulate cellular tropism independently of viral receptor expression. This antibody recognizes both IFITM2 and IFITM3.

Western blot with IFITM3 Polyclonal antibody at dilution of 1:2000.lane 1:Hela whole cell lysate, lane 2:293 T whole cell lysate, lane 3:Mouse Liver, lane 4:Mouse Heart,lane 5:Rat Liver

Immunohistochemistry of paraffin-embedded Rat kidney using IFITM3 Polyclonal Antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded Mouse lung using IFITM3 Polyclonal Antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded Human lung cancer using IFITM3 Polyclonal Antibody at dilution of 1:200

Immunofluorescence analysis of Hela cells using IFITM3 Polyclonal Antibody at dilution of 1:100

Immunofluorescence analysis of Hela cells using ifitm3 Polyclonal Antibody at dilution of 1:100

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