(KO Validated) SCD Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IF
Verified Samples |
Verified Samples in WB: H460, HeLa, Mouse liver Verified Samples in IF: U-2OS |
Dilution | WB 1:500-1:2000, IF 1:50-1:100 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | A synthetic peptide of human SCD (NP_005054.3). |
Abbre | SCD |
Synonyms | FADS5, MSTP008, SCD, SCD1, SCDOS, hSCD1 |
Swissprot | |
Calculated MW | 41 kDa |
Observed MW | 38 kDa |
Cellular Localization | Endoplasmic reticulum membrane. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Background | This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. |
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CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing
IF: 7.422