Lamin B1 Polyclonal Antibody
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Price:
Size:
100 μL
25 μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC;IF
| Verified Samples |
Verified Samples in WB: HepG2, Rat heart, Mouse kidney, Rat brain, Mouse lung, Mouse spleen Verified Samples in IHC: Human breast cancer, Mouse liver, Human uterus, Human liver Verified Samples in IF: HepG2 |
| Dilution | WB 1:250-1:500, IHC 1:200-1:600 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Rat Lamin-B1 protein expressed by E.coli |
| Abbre | Lamin B1 |
| Synonyms | ADLD, LMN, LMN2, LMNB, LMNB1, Lamin-B1, Lmnb1, MGC111419, OTTHUMP00000159218, lamin B1 |
| Swissprot | |
| Calculated MW | 67 kDa |
| Observed MW | 72 kDa |
| Cellular Localization | Nucleus inner membrane. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). |
Western Blot analysis of HepG2 cell using Lamin B1 Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of Rat heart and Rat brain using Lamin B1 Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of Mouse kidney, Mouse lung and Mouse spleen using Lamin B1 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human liver tissue using Lamin-B1 Polyclonal Antibody at dilution of 1:600(×400)
Immunohistochemistry of paraffin-embedded Human breast cancer using Lamin B1 Polyclonal Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded Mouse liver using Lamin B1 Polyclonal Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded Human uterus using Lamin B1 Polyclonal Antibody at dilution of 1:100(Elabscience Product Detected by Lifespan).
Immunofluorescence analysis of HepG2 cells using Lamin B1 Polyclonal Antibody at dilution of 1:200
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Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response
IF: 5.682
