MPO Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: IHC;IF
Verified Samples |
Verified Samples in IHC: Human liver, Mouse bone, Human spleen Verified Samples in IF: Human liver |
Dilution | IHC 1:500-1:1000, IF 1:200-1:500 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse MPO |
Abbre | MPO |
Synonyms | 84 kDa myeloperoxidase, 89 kDa myeloperoxidase, EC 1.11.1.7, EC1.11.2.2, MPO, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain, PERM, fj80f04, mpx, myeloid-specific peroxidase, wu:fj80f04 |
Swissprot | |
Cellular Localization | Lysosome |
Concentration | 0.81 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Immunology |
Conjugation | Unconjugated |
Background | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules.Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain.The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains.This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. |
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A murine model of eosinophilic chronic rhinosinusitis with nasal polyposis inducing neuroinflammation and olfactory dysfunction
IF: 14.200Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2024)PMID:38494093Reactivity:MouseSample Type:nasal septum tissue