PDGFB Polyclonal Antibody-Elabscience伊莱瑞特【官网】

PDGFB Polyclonal Antibody

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货号：E-AB-70120
说明书

说明书

Price: ¥3300.00 ¥2220.00 ¥1380.00

Size:

200 μL 120 μL 60 μL

宿主： Rabbit
反应性： Mouse;Rat
应用性： WB;IHC;IF

Verified Samples	Verified Samples in WB: Mouse heart, Mouse lung, Mouse kidney, Mouse brain, Rat heart, Rat lung, Rat brain Verified Samples in IHC: Mouse pancreas Verified Samples in IF: Rat pancreas
Dilution	WB 1:500-1:2000, IHC 1:200-1:400
Clonality	Polyclonal
Isotype	IgG
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse PDGFB
Abbre	PDGFB
Synonyms	Becaplermin, PDGF 2, PDGF B chain, PDGF subunit B, PDGF-2, PDGF2, PDGFB, Pdgfb, Platelet derived growth factor 2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, Proto-oncogene c-Sis, S
Calculated MW	27 kDa
Observed MW	27 kDa
Cellular Localization	Endoplasmic reticulum, endoplasmic reticulum lumen, Extracellular region or secreted, extracellular matrix, extracellular region, extracellular space, Golgi apparatus, Golgi lumen, Golgi membrane, Plasma Membrane, basolateral plasma membrane, Other locations: cell surface, cytoplasm, platelet alpha granule lumen.
Concentration	410 μg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4.
Purification Method	Affinity purification
Research Areas	Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction
Conjugation	Unconjugated
Background	The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Western Blot analysis of various samples using PDGFB Polyclonal Antibody at dilution of 1:1000.

Immunohistochemistry analysis of paraffin-embedded mouse pancreas using PDGFB Polyclonal Antibody at dilution of 1:200.

Immunohistochemistry analysis of paraffin-embedded Rat pancreas using PDGFB Polyclonal Antibody at dilution of 1:200.

E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1010	Goat Anti-Rabbit IgG(H+L)(Cyanine3 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1014	Goat Anti-Rabbit IgG(H+L)(FITC conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1060	Goat Anti-Rabbit IgG(H+L)(Elab Fluor® 594 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1075	Goat Anti-Rabbit IgG(H+L)(Elab Fluor® 647 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1099	Elab Fluor® Violet 450-Goat Anti-Rabbit IgG(H+L)	500 μL , 120 μL , 1 mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500 μL , 120 μL , 1 mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50 Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50 Assays