Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody
Price:
Size:
120 μL
60 μL
20 μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p;IF
| Verified Samples |
Verified Samples in WB: Mouse lung, Mouse liver, Rat kidney, HepG2, HepG2, 3T3, 3T3 Verified Samples in IHC: Human colon Verified Samples in IF: Mouse liver |
| Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human p38 around the phosphorylation site of Thr180/Tyr182 |
| Abbre | p38 (phospho Thr180/Tyr182) |
| Synonyms | CSAID Binding Protein 1, CSAID binding protein, CSAID-binding protein, CSBP, CSBP 1, CSBP 2, CSBP1, CSBP2, CSPB1, Csaids binding protein, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14 |
| Swissprot | |
| Calculated MW | 41 kDa |
| Observed MW | 38 kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Background | MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing. |
Western Blot analysis of various cells with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human colon tissue with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:200
Immunofluorescence analysis of Mouse liver tissue with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:200
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Hydroxyurea inhibits proliferation and stimulates apoptosis through inducible nitric oxide synthase in erythroid cells
IF: 6.900 -
Pyrazole derivatives ameliorate synovial inflammation in collagen-induced arthritis mice model via targeting p38 MAPK and COX-2
IF: 3.100Journal： NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2024)Reactivity：MouseSample Type：ankle joint tissue -
Empagliflozin demonstrates cytotoxicity and synergy with tamoxifen in ER-positive breast cancer cells: anti-proliferative and anti-survival effects
IF: 3.100Journal： NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2024)Reactivity：Human -
Long-lasting postoperative analgesia with local anesthetic-loaded hydrogels prevent tumor recurrence via enhancing CD8+T cell infiltration
IF: 10.200Journal： JOURNAL OF NANOBIOTECHNOLOGY (2023)PMID：36765361Reactivity：MouseSample Type：spinal dorsal horn -
Targeting Nrf2 with 3?H-1,2-dithiole-3-thione to moderate OXPHOS-driven oxidative stress attenuates IL-17A-induced psoriasis
IF: 7.500 -
Alginate/chitosan/diallyl disulfide nanoparticles: Synthesis, characterization and their anti-inflammatory efficacy on TPA-induced acute mouse ear inflammation
IF: 5.500Journal： Carbohydrate Polymer Technologies and Applications (2023)Reactivity：MouseSample Type：ears -
Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin-deficient mice
IF: 14.260Journal： EMBO Molecular Medicine (2022)Reactivity：MouseSample Type：Tibialis anterior skeletal muscles ,colonic tissues -
Mesentery AjFGF4–AjFGFR2–ERK pathway modulates intestinal regeneration via targeting cell cycle in echinoderms
IF: 8.755 -
miR-30a targets STOX2 to increase cell proliferation and metastasis in hydatidiform moles via ERK, AKT, and P38 signaling pathways
IF: 6.429Journal： Cancer Cell International (2022)PMID：35246136Reactivity：HumanSample Type：hydatidiform mole tissues ,normal placenta -
Dehydrozingerone promotes healing of diabetic foot ulcers: a molecular insight
IF: 5.908Journal： Journal of Cell Communication and Signaling (2022)PMID：36280629Reactivity：RatSample Type：foot ulcer
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