Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody
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- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p;IF
| Verified Samples |
Verified Samples in WB: Mouse lung, Mouse liver, Rat kidney, HepG2, HepG2, 3T3, 3T3 Verified Samples in IHC: Human colon Verified Samples in IF: Mouse liver |
| Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human p38 around the phosphorylation site of Thr180/Tyr182 |
| Abbre | p38 (phospho Thr180/Tyr182) |
| Synonyms | CSAID Binding Protein 1, CSAID binding protein, CSAID-binding protein, CSBP, CSBP 1, CSBP 2, CSBP1, CSBP2, CSPB1, Csaids binding protein, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14 |
| Swissprot | |
| Calculated MW | 41 kDa |
| Observed MW | 38 kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Background | MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing. |
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