SNAI1 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Monkey
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB: 3T3 Verified Samples in IF: Rat spleen |
Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthesized peptide derived from human SNAI 1 around the non-phosphorylation site of Ser246. |
Abbre | SNAI 1 |
Synonyms | Drosophila, Protein sna, Protein snail homolog, Protein snail homolog 1, SLUGH2, SNA, SNAH, SNAI, SNAI1, SNAIL, Sna protein, Snail 1 homolog, Snail 1 zinc finger protein, Snail family transcriptional repressor 1, Snail homolog 1 (Drosophila), dJ710H13.1, homo, snai1 |
Swissprot | |
Calculated MW | 29 kDa |
Observed MW | 29 kDa |
Cellular Localization | Nucleus. Cytoplasm. Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. |
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