TNF alpha Polyclonal Antibody

Price:
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB: Jurkat Verified Samples in IF: Human stomach |
Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthesized peptide derived from the Internal region of human TNF-α |
Abbre | TNF-α |
Synonyms | APC1, APC1 protein, Cachectin, DIF, Differentiation inducing factor, Macrophage cytotoxic factor, TNF, TNF superfamily, TNF-a, TNF-alpha, TNFA, TNFSF2, Tnf, Tumor n, Tumor necrosis factor, Tumor necrosis factor alpha, macrophage derived, member 2, monocyte derived |
Swissprot | |
Calculated MW | 26 kDa |
Observed MW | 16 kDa |
Cellular Localization | Secreted and Cell membrane. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Immunology, Signal Transduction |
Conjugation | Unconjugated |
Background | Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. |
-
Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease
IF: 5.2Journal: Frontiers in Endocrinology (2023)PMID:37435490Reactivity:MouseSample Type:orbital tissue -
Cycas pectinata stimulates germ cell proliferation in mouse testes
IF: 4.400Journal: PROCESS BIOCHEMISTRY (2023)Reactivity:MouseSample Type:testis -
Anti-Pyretic, Analgesic, and Anti-Inflammatory Activities of Meloxicam and Curcumin Co-Encapsulated PLGA Nanoparticles in Acute Experimental Models
IF: 4.1 -
Resveratrol may dose-dependently modulate nephrin and OTULIN levels in a doxorubicin-induced nephrotoxicity model
IF: 3.2 -
Implications of deltamethrin on hematology, cardiac pathology, and gene expression in Nile tilapia (Oreochromis niloticus) and its possible amelioration with Shatavari (Asparagus racemosus)
IF: 2.2Journal: VETERINARY RESEARCH COMMUNICATIONS (2023)PMID:37930611Reactivity:FishSample Type:heart tissue -
Neutrophils direct preexisting matrix to initiate repair in damaged tissues
IF: 31.250 -
Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin-deficient mice
IF: 14.260Journal: EMBO Molecular Medicine (2022)Reactivity:MouseSample Type:Tibialis anterior skeletal muscles ,colonic tissues -
Macrophage-Orbital Fibroblast Interaction and Hypoxia Promote Inflammation and Adipogenesis in Graves’ Orbitopathy
IF: 5.051 -
α- MSH Plays Anti-inflammatory and Anti-fungal Role in Aspergillus Fumigatus Keratitis
IF: 2.424 -
Synergistic neuroprotective effects of hyperbaric oxygen and methylprednisolone following contusive spinal cord injury in rat
IF: 1.985Journal: JOURNAL OF SPINAL CORD MEDICINE (2021)Reactivity:RatSample Type:spinal cord tissue

暂无文件,请在搜索框输入识别码查询相关文件

名称 | 状态 | 有效期至 | 操作 | |
---|---|---|---|---|
{{item.文件名}} | {{item.status_str}} | {{item.timestamp_str}} | 点击查看 点击预览 |
*注:请在有效期内下载相关文件,过期后页面内将不提供文件下载及预览!